4.4· 249 reviews

L-Lysine

A plant-based amino acid the body uses to build collagen and support the structural health of skin, tissue, and bone.

  • Vegan
  • Non-GMO
  • Soy-Free
  • Gluten-Free
  • Made in USA

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Supplement Facts

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 50

Nutrient Amount Per Serving % DV*
L-Lysine (as L-Lysine hydrochloride) 500mg *

* Daily Value not established.

Other Ingredients: Capsule (Vegetable Source), Magnesium Stearate (Vegetable Source), Cellulose.

How to Use
Take 1 capsule daily with food.
Research

The studies below reference peer-reviewed research on the key active ingredients in this product. These are ingredient-level studies.

L-Lysine (as L-Lysine hydrochloride)

  • Griffith et al., 1987 · Dermatologica

    Randomized, double-blind, placebo-controlled crossover trial; n=52; 6 months; participants with recurrent herpes labialis

    Participants with recurrent herpes labialis who received L-lysine supplementation (1,248 mg/day) showed statistically significant reductions in frequency, severity, and healing time of herpes recurrences compared to those who received placebo; the study authors noted that benefits were not observed in participants who reported high dietary arginine intake.

  • Smriga et al., 2007 · Proceedings of the National Academy of Sciences

    Randomized, double-blind, placebo-controlled community-based trial; n=108; 3 months; adults with lysine-deficient dietary patterns

    Participants with lysine-deficient dietary patterns who received L-lysine-fortified wheat showed statistically significant reductions in anxiety and stress-related measures compared to those who did not receive fortified wheat; the population studied had baseline lysine deficiency and results may not generalize to lysine-sufficient individuals.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

How it works

Every ingredient, chosen with intention.

Here's what's in this bottle - and why each ingredient earned its place in the formula.

  1. L-Lysine

    L-Lysine as L-lysine hydrochloride

    One of the nine essential amino acids the body cannot synthesize on its own, serving as a building block for proteins including collagen. Delivered in free-form as the HCl salt, a stable, water-soluble compound absorbed directly without requiring digestion to liberate it from a protein chain first.

    Why we chose it

    Lysine is the limiting amino acid in most plant-based diets, it's the first essential amino acid to fall short when eating primarily grains with few legumes. At 500mg of free-form lysine HCl per capsule, this provides a consistent, rapidly absorbed daily amount without restructuring the whole diet.

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Questions, answered

What customers often ask.

Why is lysine the amino acid most plant-based eaters need?
Lysine is the limiting amino acid in grains: rice, wheat, oats, and corn all have low lysine relative to the other essential amino acids. Plant-based eaters who rely heavily on grains without balancing with legumes are most likely to fall short. Supplementing with free-form lysine HCl fills that gap directly.
Should I take this with food or on an empty stomach?
Free-form amino acids are typically absorbed more rapidly on an empty stomach. Some people prefer taking it 30 minutes before a meal. That said, taking it with a small amount of food is fine if you prefer, it's absorbed either way.
Can I take this alongside zinc or vitamin C?
Yes, L-Lysine, zinc, and vitamin C are frequently combined and do not negatively interact. All three are common daily supplements with complementary roles: lysine as a structural amino acid, zinc and vitamin C as cofactors for collagen synthesis and immune function.
How long before I notice a difference?
L-Lysine is an essential amino acid, its role is foundational rather than acute. If you've been running a chronic dietary deficit, bringing levels up consistently over four to eight weeks tends to be when most people who track their nutrition notice a shift. There's no rapid observable effect like a stimulant.
What does 'free form HCl' mean?
L-Lysine hydrochloride is lysine bonded to hydrochloric acid as a stabilizing salt, the same form your stomach acid would produce naturally. 'Free form' means it's not locked inside a protein chain that requires digestion to release it first, so absorption is more direct and rapid.
Is this safe to take daily long-term?
L-Lysine is an essential amino acid found naturally in food and is considered safe for daily supplementation at 500mg doses. Please consult your healthcare provider if you are pregnant, breastfeeding, or managing a kidney condition, high-dose amino acid supplements generally warrant monitoring in those contexts.

What customers say

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