Participants with functional dyspepsia who received a deglycyrrhizinated licorice preparation (GutGard®) showed statistically significant reductions in dyspepsia symptom scores compared to those who received placebo (P < 0.05); DGL preparations have had the glycyrrhizin component removed to reduce risks associated with high-dose whole-licorice intake.
Participants with self-reported unsatisfactory sleep who received glycine supplementation (3g) before bedtime showed statistically significant improvements in subjective sleep quality, daytime sleepiness, and fatigue scores compared to those who received placebo; small sample size limits generalizability of these findings.
Participants whose sleep was experimentally restricted who received glycine (3g/day) showed statistically significant reductions in daytime sleepiness and psychomotor vigilance test fatigue compared to those who received placebo; results were specific to the sleep-restricted condition and the dose studied (3g) exceeds the amount in this product.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
DGL Licorice$17.84
How it works
Every ingredient, chosen with intention.
Here's what's in this bottle - and why each ingredient earned its place in the formula.
A concentrated extract of licorice root processed to remove glycyrrhizin, the compound responsible for licorice root's potential effects on blood pressure and hormone balance at sustained high doses, while retaining the root's other active compounds.
Why we chose it
760mg per serving is a meaningful dose. The deglycyrrhizination step removes the one limiting component of whole licorice root, making a high, consistent daily amount practical without the constraints that come with glycyrrhizin accumulation over time.
L-Glycine
a conditionally essential amino acid
The simplest amino acid, used as a building block for proteins including collagen, and as a precursor to compounds the body produces. Included here as a functional co-ingredient alongside the licorice extract.
Why we chose it
Glycine is one of the few amino acids with established mucosal-relevant properties in cell research, pairing logically with a formula designed for digestive support.
A daily plant-based fiber gummy with inulin from chicory root, formulated to support the growth of beneficial bacteria in the gut.
Questions, answered
What customers often ask.
What does DGL mean and why does it matter?
DGL stands for deglycyrrhizinated licorice, licorice root that has had glycyrrhizin removed through a water extraction process. Glycyrrhizin at high doses can affect blood pressure and electrolyte balance. Removing it makes a 760mg daily dose practical for ongoing digestive support without those concerns.
Should I take these capsules before or after eating?
Most people take DGL before meals for proactive stomach comfort. If you experience occasional post-meal discomfort, taking it shortly after eating is also common. There's flexibility, the goal is to have it present in the GI tract when you need it most.
How long before I notice a difference?
A randomized controlled trial on a DGL preparation showed statistically significant reductions in dyspepsia symptom scores at 30 days compared to placebo. Daily consistent use tends to show the clearest results, sporadic use is less studied. Individual timelines vary.
Is this safe if I take blood pressure medication?
Please consult your healthcare provider before taking DGL if you're on blood pressure medication, diuretics, or any cardiac medications. While the glycyrrhizin has been removed, your healthcare provider is best positioned to advise on supplement interactions specific to your medication regimen.
How is this different from the DGL Licorice Chewables?
This capsule formula delivers 760mg of DGL extract per serving, almost double the 400mg in the chewable version. If you prefer swallowing a capsule and want a higher per-serving dose, this is the option. The chewable version activates pre-digestively but at a lower dose per serving.
What is L-Glycine doing in this formula?
Glycine is an amino acid with naturally occurring properties relevant to digestive tissue. It's included as a functional co-ingredient alongside the licorice extract, not as the primary active ingredient, but as a complement to DGL's support for the stomach's mucosal environment.
What customers say
Results, backed by reviews.
5 stars: 125 (64%)
4 stars: 44 (23%)
3 stars: 18 (9%)
2 stars: 7 (4%)
1 star: 0 (0%)
p
pennylane
Did not help much
Tastes like chalk. Didnt do much for me.
e
eli_74
Before a big meal
I started keeping this near the dining table and take it before meals that I know will be heavier than usual. It is a small thing, but I feel more comfortable afterward. No chalky taste and the bottle lasts a while.
K
KYLE J.
Before meals
Coffee and a rushed lunch can leave me feeling pretty rough afterward. I started keeping these in the kitchen and chew one before a heavier meal. The flavor is a little sweeter than I expected, but not bad. I have used them for about a month and they have become one of those small habits I notice when I forget. My partner tried one too and immediately asked why it tasted like candy, so fair warning there. The chewable format is the reason I picked this version over another bottle of capsules.
N
N. Price
Just okay for me
I wanted to like these more. I used one before meals after coffee because that is usually when I notice the burn, and it helped a little some days. Other days I could not tell much at all. The taste is fine and the tablets are easy enough to use, but I kept wishing the effect was more reliable. Not horrible, just not a product I am excited to reorder right now.
D
Daniel Ortiz
not for me
didnt help enough. not buying again
P
Priya S.
Helpful before meals
My reflux episodes are usually triggered by late meals or too much coffee. I started taking this before meals and the burning feeling is less frequent. I still watch what I eat, obviously, but this has earned a spot in the cabinet.
P
Priya
Good for long-term use
Unlike PPIs, DGL is safe for long-term use because it supports the stomach lining rather than suppressing acid production. That distinction matters to me. And the results are real.
K
Karen
Ulcer recovery support
Dealing with a peptic ulcer. Doctor approved DGL as complementary support alongside my medication. Stomach is healing well and I have much less daily discomfort.
J
Jessica
Finally something gentle
Tried omeprazole for years. Hate the long-term effects. DGL was recommended as a gentler alternative. My stomach is noticeably calmer.
p
pk_22
Seven years of GERD, finally managed
I have had GERD for seven years. I've been through every OTC acid reducer on the market, two different PPIs, and dietary elimination protocols that were miserable and unsustainable. My naturopath suggested DGL licorice when I mentioned I wanted to stop PPIs long term.
The mechanism made sense to me — DGL supports mucus production in the stomach lining which creates a protective barrier, rather than suppressing the acid itself. I started taking it before meals in December and stayed consistent through January.
By week 3 I noticed I was reaching for antacids less. By week 6 my baseline stomach discomfort — the background burning that was just always there — had significantly reduced. By week 10 I had reduced my PPI to every other day under my doctor's supervision.
This is the closest I've gotten to managing my GERD naturally. I'm not claiming it works for everyone but it's the most effective non-pharmaceutical approach I've found after seven years.
p
pk_22
Stomach lining support
My gastroenterologist recommended DGL to help with gut lining repair after an H. pylori infection. Been on it 8 weeks and my follow-up scope looked good.
K
Karen
Reduced PPI use
Working with my doctor to reduce omeprazole dependence. DGL is the bridge. Down from daily PPI to 3x per week. Stomach managing well.
S
Sofia
Pairs well with probiotics
Taking alongside my probiotic as a comprehensive gut health approach. The DGL protects the lining while the probiotic restores the flora. My gut is the best it's been in years.
p
pk_22
My gastro approved it
Asked my gastroenterologist if DGL was appropriate. She said yes and explained the mechanism. Ten weeks in. Stomach is calmer, reflux is reduced.
L
LINDA P.
Ditched my antacids
Ditched the antacids. DGL is doing the work.
G
GINA M.
Good quality formula
DGL means the glycyrrhizin compound is removed — the form that can affect blood pressure. This has the correct safe form. Taking confidently.
R
Robert Kim
Acid reflux under control
Acid reflux under control for the first time in years.
L
Linda
Less burning after coffee
Coffee is my reflux trigger. Started taking DGL before my morning cup and the burning is significantly reduced. Still not zero but way more manageable. Small change, big difference.
D
DIANE F.
Less burning is meaningful
I was taking tums multiple times a day. Started DGL and cut my antacid use by about 80% in the first month. Still keep tums for emergencies but rarely need them now.
N
Nicole B.
Natural option that works
Skeptical of natural alternatives to acid medication. But DGL has actual research behind it and I can feel the difference. GI tract is calmer and I have less discomfort after eating.
D
David C.
Works before meals
Taking one before big meals or spicy food. Post-meal heartburn is dramatically reduced. Not zero but way better.
M
Michael Torres
Consistent daily support
Not a dramatic rescue medication. More like a consistent daily support that keeps my stomach comfortable. That slow steady improvement is exactly what I needed.
J
Jennifer M.
Helped during stressful months
Stress always triggers my acid reflux. Went through a rough January and kept taking DGL throughout. The reflux was manageable even during the stressful stretch.
H
H.I.
great supplement for sensitive stomachs
i have a very sensitive stomach. most supplements bother it. DGL is one of the few that is truly gentle and effective
p
ppi_reduction_plan
using to reduce PPI dependency
working with my doctor to reduce my PPI dose. DGL is part of that protocol. too early to give final verdict but 6 weeks in it seems to be helping maintain comfort as i step down the prescription
n
nurse_reviewer
the no-BP-elevation point matters
im a nurse. the fact that DGL removes the glycyrrhizin is medically important. regular licorice is contraindicated for many patients. this isnt. matters for long-term use
P
P.Q.
stomach feels healed
after months of pain and burning my stomach actually feels normal now. i dont take that for granted anymore
V
V.W.
reduced inflammation i can feel
hard to measure but something about how my stomach feels day to day is different. less inflamed. less reactive. more comfortable
Y
Y.Z.
works for prevention not rescue
if you're taking it after symptoms start you wont get much. take before eating. works as prevention
I
I.J.
good for gastritis
gastritis is rough and conventional medicine wasnt fully helping. DGL has been a great complement to my protocol
E
E.F.
stomach lining protecting itself again
feels like my stomach is doing what a healthy stomach should do - protecting itself. the mucus layer is rebuilding. less raw, less reactive
t
three_month_rule
needs 3+ months to fully assess
dont give up at 4 weeks. at 3 months the results are much more apparent. patience pays off
