* Percent Daily Values are based on a 2,000 calorie diet.
** Daily Value not established.
Other Ingredients: Xylitol, vegetable stearic acid, natural tropical flavors, cellulose, citric acid, turmeric root (for color), silica, vegetable magnesium stearate and high purity steviol glycosides.
How to Use
Chew 2 tablets after a heavy meal to support digestion.
Research
The studies below reference peer-reviewed research on the key active ingredients in this product. These are ingredient-level studies.
Papain (papaya enzyme)
Muss et al., 2013 · Neuro Endocrinology Letters
Double-blind, placebo-controlled RCT; small sample (N≈13); 40 days
Participants who received a standardized papaya preparation (Caricol®) showed statistically significant improvements in constipation and bloating scores compared to those who received placebo; the study authors noted that small sample size limited statistical power for some outcomes including heartburn.
Randomized controlled trial; sample size not reported in abstract; 14 weeks; fermented papaya preparation (6g/day)
Participants who received a fermented papaya preparation daily showed significantly reduced C-reactive protein levels (P=0.018) and improved LDL/HDL cholesterol ratio (P=0.042) compared to baseline; the preparation studied was a fermented form and results may not directly translate to unfermented raw papain.
Castell et al., 1997 · American Journal of Physiology
Double-blind RCT; n=19 healthy men; multi-dose phase over 48 hours
Participants who received oral bromelain showed measurable intact enzyme in plasma with a half-life of 6–9 hours, demonstrating that bromelain is absorbed across the gastrointestinal epithelium and retains enzymatic activity in circulation following oral dosing.
A systematic review of randomized controlled trials found that participants who received bromelain supplementation showed reductions in inflammatory markers including IL-6, TNF-α, and CRP in most included studies, with gastrointestinal adverse effects reported as well-tolerated across the reviewed trials.
Participants with mild-to-moderate ulcerative colitis who received 400mg/day of bromelain showed significantly larger reductions in disease activity scores compared to those who received placebo (P < 0.001); quality-of-life measures did not differ significantly between groups in this population.
Participants with functional dyspepsia who received a multienzyme complex containing amylase, protease, and lipase (DigeZyme®) showed statistically significant improvements across all measured efficacy outcomes compared to those who received placebo (P ≤ 0.04), with no adverse events reported; enzyme blend composition may differ from the blend in this product.
Participants with functional dyspepsia who received a multi-enzyme supplement containing amylase, protease, and lipase showed statistically significant improvements in quality-of-life scores, pain severity, and sleep quality compared to those who received placebo, with no side effects reported.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Vegan Daily Cleanse Papaya Enzymes$20.39
How it works
Every ingredient, chosen with intention.
Here's what's in this bottle - and why each ingredient earned its place in the formula.
Papain
from ripe Carica papaya fruit
A plant-sourced digestive enzyme that helps break down proteins into smaller peptides and amino acids as food moves through the stomach and small intestine.
Why we chose it
Sourced directly from papaya fruit at a meaningful 200mg dose, not a synthetic substitute, so it delivers the full enzymatic activity the plant naturally produces.
Bromelain
from pineapple stem
A proteolytic enzyme from pineapple that works alongside papain to help break down proteins across a wider range of digestive conditions.
Why we chose it
Bromelain is active across a different pH range than papain, so pairing them gives the formula broader enzymatic coverage throughout the digestive tract, not just in one compartment.
Whole Papaya Fruit
Carica papaya
The whole fruit matrix adds naturally occurring papaya compounds beyond the concentrated enzyme extract, reflecting what you'd encounter in the real fruit.
Why we chose it
Rather than relying solely on an isolated enzyme, Yuve includes whole papaya fruit so the formula carries the fuller plant profile, the way nature packages it, not just one extracted compound.
Plant Enzyme Blend
amylase, protease, and lipase from plant sources
Three additional enzymes that together help the body break down carbohydrates, proteins, and fats found in a typical mixed meal.
Why we chose it
Most meals are a mix of carbs, fats, and protein, a formula focused only on one macronutrient type leaves work undone. This broad-spectrum blend supports digestion across all three.
A chewable plant-based licorice root extract with glycyrrhizin removed, formulated to support stomach comfort and everyday digestive ease.
Questions, answered
What customers often ask.
How long before I notice a difference?
Many people notice a shift in how they feel after heavier meals within the first week of daily use. For more consistent digestive comfort, studies on papain and the plant enzyme blend suggest two to four weeks of regular use tends to show the clearest difference. Results vary by diet and individual gut chemistry.
Should I take these with food or on an empty stomach?
With or right after meals. Digestive enzymes help your body break down what you’ve just eaten, they need food present to do that work. Taking them on an empty stomach leaves them without anything to act on.
Can I take these alongside your Probiotic Gummies?
Yes, they’re complementary, not redundant. These tablets support the breakdown of food as it moves through the stomach and small intestine. The probiotic gummies work further down, supporting the gut’s microbial environment. Most people who take both do so daily without issue.
Is this safe during pregnancy or while breastfeeding?
Please consult your healthcare provider before adding any supplement during pregnancy or breastfeeding. This formula uses ripe papaya extract, not unripe papaya, which carries different considerations, but supplement decisions during pregnancy are always best made alongside your doctor.
Are these sweetened with sugar? What do they taste like?
No sugar. These are sweetened with xylitol and steviol glycosides (from stevia), making them suitable for those watching sugar intake. They’re chewable tablets with a mild tropical flavor, light enough that most people find them easy to take right after a meal.
Why does this combine papain AND bromelain, isn’t one enough?
Papain and bromelain both help break down proteins, but each is most active at slightly different points along the digestive tract. Pairing them gives broader enzymatic coverage from the stomach through the small intestine. The plant enzyme blend, amylase, protease, and lipase, extends that to carbohydrates and fats as well.
Told my GI doctor I was taking papaya enzymes at my last appointment. She said the evidence was good and to keep going. Five months later my GI appointment was the best I've had.
A
A.R.
I was never able to take any digestive enzymes before they were always just too strong. They made me worse. This product is amazing. I'm finally digesting.
D
DIANE F.
Less gas than ever
my partner definitely appreciates this one lol. gas was embarrassing and constant. these enzymes reduced it dramatically. meal times and after are so much more comfortable for everyone.
L
L. Barnes
Works FAST
Works fast. Felt different within days.
J
Jennifer
For protein digesters
take these with every protein meal. less gas, less bloating, better energy after eating. the papain enzyme breaks down protein efficiently and my gut reflects that.
Save $14.72
