4.5· 789 reviews

Vegan Daily Cleanse Papaya Enzymes

A plant-sourced enzyme blend that helps your body break down proteins, fats, and carbs from everyday meals.

  • Vegan
  • Non-GMO
  • Soy-Free
  • Gluten-Free
  • Made in USA
Size

In stock · ships in 1 business day

60-day money-back guarantee · Free shipping $75+

Supplement Facts

Supplement Facts

Serving Size: 2 chewable tablets

Servings Per Container: 45

Nutrient Amount Per Serving % DV*
Total Carbohydrate <1g <1%
Papain (from Papaya) 35TU/mg 200mg *
Papaya fruit 10mg *
Bromelain (from pineapple) 1.6 GDU/mg 10mg *
Plant Enzyme Blend (supplying amylase, protease, lipase) 10mg *

* Percent Daily Values are based on a 2,000 calorie diet.

** Daily Value not established.

Other Ingredients: Xylitol, vegetable stearic acid, natural tropical flavors, cellulose, citric acid, turmeric root (for color), silica, vegetable magnesium stearate and high purity steviol glycosides.

How to Use
Chew 2 tablets after a heavy meal to support digestion.
Research

The studies below reference peer-reviewed research on the key active ingredients in this product. These are ingredient-level studies.

Papain (papaya enzyme)

  • Muss et al., 2013 · Neuro Endocrinology Letters

    Double-blind, placebo-controlled RCT; small sample (N≈13); 40 days

    Participants who received a standardized papaya preparation (Caricol®) showed statistically significant improvements in constipation and bloating scores compared to those who received placebo; the study authors noted that small sample size limited statistical power for some outcomes including heartburn.

  • Somanah et al., 2012 · Preventive Medicine

    Randomized controlled trial; sample size not reported in abstract; 14 weeks; fermented papaya preparation (6g/day)

    Participants who received a fermented papaya preparation daily showed significantly reduced C-reactive protein levels (P=0.018) and improved LDL/HDL cholesterol ratio (P=0.042) compared to baseline; the preparation studied was a fermented form and results may not directly translate to unfermented raw papain.

Bromelain (pineapple enzyme)

  • Castell et al., 1997 · American Journal of Physiology

    Double-blind RCT; n=19 healthy men; multi-dose phase over 48 hours

    Participants who received oral bromelain showed measurable intact enzyme in plasma with a half-life of 6–9 hours, demonstrating that bromelain is absorbed across the gastrointestinal epithelium and retains enzymatic activity in circulation following oral dosing.

  • Pereira et al., 2023 · Clinical Nutrition ESPEN

    Systematic review of RCTs; 7 eligible trials included; 1–16 week durations; dosages 99.9–1,200 mg/day

    A systematic review of randomized controlled trials found that participants who received bromelain supplementation showed reductions in inflammatory markers including IL-6, TNF-α, and CRP in most included studies, with gastrointestinal adverse effects reported as well-tolerated across the reviewed trials.

  • Delgarm et al., 2025 · Scientific Reports

    Randomized, triple-blind, placebo-controlled trial; n=70; 8 weeks; participants with mild-to-moderate ulcerative colitis

    Participants with mild-to-moderate ulcerative colitis who received 400mg/day of bromelain showed significantly larger reductions in disease activity scores compared to those who received placebo (P < 0.001); quality-of-life measures did not differ significantly between groups in this population.

Plant Enzyme Blend (amylase, protease, lipase)

  • Majeed et al., 2018 · Journal of Medicinal Food

    Randomized, double-blind, placebo-controlled trial; n=40; 60 days; participants with functional dyspepsia

    Participants with functional dyspepsia who received a multienzyme complex containing amylase, protease, and lipase (DigeZyme®) showed statistically significant improvements across all measured efficacy outcomes compared to those who received placebo (P ≤ 0.04), with no adverse events reported; enzyme blend composition may differ from the blend in this product.

  • Ullah et al., 2023 · Biomedicine & Pharmacotherapy

    Randomized, double-blind, placebo-controlled trial; n=120; 2 months; participants with functional dyspepsia

    Participants with functional dyspepsia who received a multi-enzyme supplement containing amylase, protease, and lipase showed statistically significant improvements in quality-of-life scores, pain severity, and sleep quality compared to those who received placebo, with no side effects reported.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

How it works

Every ingredient, chosen with intention.

Here's what's in this bottle - and why each ingredient earned its place in the formula.

  1. Papain

    Papain from ripe Carica papaya fruit

    A plant-sourced digestive enzyme that helps break down proteins into smaller peptides and amino acids as food moves through the stomach and small intestine.

    Why we chose it

    Sourced directly from papaya fruit at a meaningful 200mg dose, not a synthetic substitute, so it delivers the full enzymatic activity the plant naturally produces.

  2. Bromelain

    Bromelain from pineapple stem

    A proteolytic enzyme from pineapple that works alongside papain to help break down proteins across a wider range of digestive conditions.

    Why we chose it

    Bromelain is active across a different pH range than papain, so pairing them gives the formula broader enzymatic coverage throughout the digestive tract, not just in one compartment.

  3. Whole Papaya Fruit

    Whole Papaya Fruit Carica papaya

    The whole fruit matrix adds naturally occurring papaya compounds beyond the concentrated enzyme extract, reflecting what you'd encounter in the real fruit.

    Why we chose it

    Rather than relying solely on an isolated enzyme, Yuve includes whole papaya fruit so the formula carries the fuller plant profile, the way nature packages it, not just one extracted compound.

  4. Plant Enzyme Blend

    Plant Enzyme Blend amylase, protease, and lipase from plant sources

    Three additional enzymes that together help the body break down carbohydrates, proteins, and fats found in a typical mixed meal.

    Why we chose it

    Most meals are a mix of carbs, fats, and protein, a formula focused only on one macronutrient type leaves work undone. This broad-spectrum blend supports digestion across all three.

Complete your bundle

Save 20% when you bundle.

Pairs well with

Complete your routine.

Probiotic Gummies editorial hero
4.6

Vegan Probiotic Gummies

A daily plant-based gummy with five billion live cultures, formulated to support a healthy balance of bacteria in the gut.

Prebiotic Fiber Gummies editorial hero
4.4

Vegan Prebiotic Fiber Gummies

A daily plant-based fiber gummy with inulin from chicory root, formulated to support the growth of beneficial bacteria in the gut.

DGL Licorice Chewables editorial hero
4.5

DGL Licorice Chewables

A chewable plant-based licorice root extract with glycyrrhizin removed, formulated to support stomach comfort and everyday digestive ease.

Questions, answered

What customers often ask.

How long before I notice a difference?
Many people notice a shift in how they feel after heavier meals within the first week of daily use. For more consistent digestive comfort, studies on papain and the plant enzyme blend suggest two to four weeks of regular use tends to show the clearest difference. Results vary by diet and individual gut chemistry.
Should I take these with food or on an empty stomach?
With or right after meals. Digestive enzymes help your body break down what you’ve just eaten, they need food present to do that work. Taking them on an empty stomach leaves them without anything to act on.
Can I take these alongside your Probiotic Gummies?
Yes, they’re complementary, not redundant. These tablets support the breakdown of food as it moves through the stomach and small intestine. The probiotic gummies work further down, supporting the gut’s microbial environment. Most people who take both do so daily without issue.
Is this safe during pregnancy or while breastfeeding?
Please consult your healthcare provider before adding any supplement during pregnancy or breastfeeding. This formula uses ripe papaya extract, not unripe papaya, which carries different considerations, but supplement decisions during pregnancy are always best made alongside your doctor.
Are these sweetened with sugar? What do they taste like?
No sugar. These are sweetened with xylitol and steviol glycosides (from stevia), making them suitable for those watching sugar intake. They’re chewable tablets with a mild tropical flavor, light enough that most people find them easy to take right after a meal.
Why does this combine papain AND bromelain, isn’t one enough?
Papain and bromelain both help break down proteins, but each is most active at slightly different points along the digestive tract. Pairing them gives broader enzymatic coverage from the stomach through the small intestine. The plant enzyme blend, amylase, protease, and lipase, extends that to carbohydrates and fats as well.

What customers say

Results, backed by reviews.

  • 5 stars: 513 (65%)
  • 4 stars: 169 (21%)
  • 3 stars: 64 (8%)
  • 2 stars: 38 (5%)
  • 1 star: 5 (1%)
N
Nadine Flores
Finally a routine I can stick with

I bought these during a stretch when every lunch seemed to sit with me until bedtime. I was skeptical because I have a cabinet full of half-used supplements and most of them either felt too harsh or were impossible to remember. For the first week I noticed basically nothing. During week two I realized I was not reaching for tea after dinner just to feel settled. By week four the difference was obvious: breakfast felt lighter, my schedule was more predictable, and I wasnt thinking about digestion all afternoon. The best part is that it has been gentle. No sudden urgency, no weird cramping, no elaborate timing. I leave the bottle beside the coffee maker and take it with breakfast. My partner asked why I had stopped complaining after takeout and I laughed because I hadnt even noticed that change myself. I still eat normally and I dont expect a supplement to erase every questionable meal, but this has quietly become one of the few things I reorder before the bottle is empty. UPDATE: two months in and STILL part of my morning routine!!

b
beckett_reads
not much for me

month 1 nothing. month 2 maybe a little more regular but honestly not enough to keep paying for it. I finished the bottle and thats it

M
MILES P.
Easy routine

I take it after breakfast. feels gentle and I dont get that heavy stuffed feeling by lunch anymore

T
Tara
Yep

Works!!!

T
Thomas Bell
Six weeks and still impressed

I started this after a stretch of travel when every meal seemed to be airport food, restaurant food, or something eaten too late at night. My normal breakfast routine disappeared and so did any sense of regularity. A friend had a bottle of these and said 'just give it a few weeks before you decide.' I rolled my eyes because I have a cabinet full of products that promised a better routine and mostly delivered clutter. Still, I began taking one each morning with water. The first week was unremarkable. During week two I noticed that lunch no longer left me wanting to loosen my waistband and lie down. Week three was when it clicked: I had gone several days without thinking about digestion at all, which is honestly the best outcome. After I got home I kept taking them with breakfast, even on weekends. Six weeks in, my mornings are more predictable and heavy meals dont seem to hang around FOREVER. There has been no harsh rush, cramping, or strange artificial feeling. It is simply gentler than the cleanse products I tried years ago. My wife asked why this bottle was actually on the counter instead of buried in the supplement drawer, and I told her 'because I remember to take the things that make a difference.' She laughed and ordered one for herself. UPDATE: we are both still using it, and I already bought a backup before the first bottle ran out 🙂

F
Felicia R.
Not much happened

month 1 nothing. month 2 maybe a slightly easier morning once or twice but not enough to justify another bottle. i took it with breakfast like the label says and didnt skip days. The capsules themselves were fine, no weird taste, no stomach upset, but I bought this for regularity and that part stayed inconsistent. Some days felt lighter after lunch, other days exactly the same as before. I even kept a note in my phone bc I thought maybe I was overlooking a slow change... nope. By the last week I was mostly annoyed that I had spent two months waiting. Giving three stars only because it was gentle and easy to swallow. Results were barely there for me

e
emmett_56
Skeptic converted

tbh I assumed this was another bottle that would sit behind the coffee until it expired. My sister left it at my apartment and told me to at least try a full month, so fine. Week one, nothing worth reporting. Week two, I noticed I wasnt feeling quite as weighed down after breakfast. By week four my morning routine felt more predictable and I was reaching for the bottle without her texts. The capsules dont have a harsh smell and they have been easy on my stomach, which matters bc other enzyme products made me queasy. I am not suddenly eating perfectly or pretending one supplement does everything. I just feel lighter after meals and more regular than I did before. ordered my own bottle yesterday, so yes she gets to say she told me so lol

L
Louis K.
ok WOW

I bought these on a whim after another heavy dinner left me feeling like a balloon. Didnt expect much because digestive supplements have been hit or miss for me. By the second week I realized I was no longer planning my evenings around that overfull feeling. I still eat normally, including the occasional ridiculous restaurant meal, but the next few hours are much easier. HUGE difference for such a small change in my breakfast routine!!

P
PATRICIA G.
Noticeably lighter after meals

I have used this product consistently for approximately five weeks. Digestion after lunch feels more comfortable, and my usual afternoon heaviness is less noticeable. No dramatic claims from me, just a steady improvement that has made it worth continuing.

M
Maribel S.
Gentle after breakfast

I take these with breakfast. feels gentle and I dont get that heavy post-meal feeling anymore

R
Renee
It works

Works.

w
wade koester

we love this product.

H
Harold T.
Still waiting

ive taken this with breakfast for almost a month. first week felt lighter after lunch, since then its been pretty inconsistent. some mornings are easier and some are exactly the same. bottle is easy to use but tbh i expected more by now

a
april_notes
Gentle once I adjusted

Started at the full serving and felt too active for two days. Half a serving for a week was better, then i moved up. Works gently now

D
DEREK M.
Quietly helpful

nothing dramatic but breakfast sits better and my mornings are more predictable now

N
Noelle
Just easy

Easy!!

D
Dennis O.
Still deciding

Month one was fine. I did not notice much at first, then it seemed a little easier after rich meals. Not a big difference for me, so I am undecided.

S
Shannon V.
Solid but mild

Good little capsules. I prefer taking them with food, otherwise I notice a mild pineapple taste.

c
clr_2009
Less heavy after dinner

Three weeks in and I feel less heavy after dinner. No dramatic stuff, just a welcome change.

M
MARTIN E.
Easy routine

Started these with breakfast. They feel gentle and fit my routine.

A
Alicia
Exactly right

Works.

N
Nadia Cole
Just okay for me

Three weeks in. Meals feel a little lighter but I was expecting more. I will finish the bottle, then decide if it is worth buying again.

f
foster_83
Works well enough

Started with one after dinner. It has been gentle and I like that it does not leave me feeling like I overdid a supplement. The price keeps it from being an automatic reorder for me.

R
Ravi M.
Back in my routine

I take this with breakfast and the after-lunch heavy feeling is noticeably less common now. Nothing dramatic, just a better everyday routine.

L
Leah
Good stuff

Love it.

J
Jonathan Reed
Not much for me

Not a big change for me. I finished the bottle and my digestion felt about the same most days. It was gentle and easy to take, but I kept waiting for the difference people mention and it never really showed up. Maybe my meals are too all over the place. I will not be buying another bottle right now.

c
clarice_9
Worth trying

I was skeptical about papaya enzymes, but taking one after a big dinner feels noticeably easier. The bottle lasts a while too.

M
Mark I.
Gentle routine

My morning routine feels lighter and I have stayed with it. Simple, gentle, no drama.

P
Paige
Simple win

Better.

N
NORA F.
Not for everyone maybe

I wanted to love this more than I did. The capsule itself is fine and I had no problem taking it, but after nearly a month I cannot say I noticed enough to justify buying it again. My meals and schedule were all over the place that month, so maybe that is part of it. I did like that it was not harsh or uncomfortable. I just kept waiting for a clearer difference after big dinners and it never really arrived for me. If you already have a steady routine you might have better luck, but mine did not change much. Packaging was good, delivery was fast, and nothing was wrong with the product. It simply did not become something I reached for. I will finish the bottle and move on.

a
alvarez.k
Quietly dependable

My husband jokes that I have a drawer full of things I try once and abandon. This one has stayed. I use it after the kind of dinner where I know I went a little too hard, and it feels gentle rather than like some aggressive cleanse. The capsules are easy for me to take, no weird aftertaste, and I dont get that urgent feeling some digestive products give me. I would call the change gradual, but after a month I noticed I was much more comfortable sticking to my normal meal schedule.